Northwestern University · PhysiologyDopamine and Cognition Lab
Jones G Parker · Evanston, Illinois
Research Focus
Dr. Jones G Parker's lab at Northwestern University focuses on understanding how dopamine affects cognition and perception, especially in relation to mental health disorders like schizophrenia. The research investigates the roles of D1 and D2 dopamine receptors in these processes and aims to explore new therapeutic strategies using cholinergic antipsychotics, which may offer benefits over traditional treatments. The lab employs advanced imaging techniques to study neural circuits and the effects of different drugs on brain activity.
dopamineschizophreniacognitionperceptionantipsychoticscholinergic receptorsD1 receptorsD2 receptorsin vivo imagingneural circuits
Research Aims
5AIM 01Investigate how excess dopamine alters neural activity in areas related to cognition and perception.
AIM 02Explore the therapeutic potential of novel cholinergic antipsychotics for treating cognitive deficits.
AIM 03Determine the distinct roles of D1 and D2 dopamine receptor activity in behavioral tasks.
AIM 04Analyze how cholinergic drugs interact with dopamine-related neural circuits.
AIM 05Elucidate the mechanisms of action of new therapies for schizophrenia-related symptoms.
Skills the Lab Values
in vivo imagingchemogeneticsmicrodialysisbehavioral testingmouse modelscalcium imaginggenetic manipulationdrug administrationneuropharmacologyelectrophysiology
Output against the department
Publications36bottom 3% of dept.276th of 286
this lab
most publishedleast published
Citations2.3kbottom 15% of dept.242nd of 286
this lab
most citedleast cited
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