University of Massachusetts-Lowell · ChemistryDenture Health Innovations Lab
Yuyu Sun · Lowell, Massachusetts
Research Focus
Dr. Yuyu Sun's lab at the University Of Massachusetts Lowell focuses on using natural salivary components to prevent oral health issues related to denture wear. The research aims to develop innovative coatings for dentures that can effectively control fungal biofilms, particularly those causing denture stomatitis. This work addresses a significant health concern for elderly and immunocompromised patients, improving their quality of life and reducing reliance on drugs with potential side effects.
denture coatingsCandida biofilmsalivary peptideslayer-by-layer self-assemblyoral healthdenture stomatitisbiocompatibilitynatural therapeutics
Research Aims
3AIM 01Develop multilayer coatings for dentures using salivary anticandidal peptides
AIM 02Evaluate the antifungal activity of the coated dentures in vitro
AIM 03Test the efficacy of the salivary protein coatings in a rat denture stomatitis model.
Skills the Lab Values
layer-by-layer assemblymultilayer coatings fabricationin vitro testinganimal modelsbiocompatibility assessmentpolymers chemistrymicrobial biofilms analysisdenture design optimizationsalivary component extraction
Output against the department
Publications117bottom 25% of dept.162nd of 216
this lab
most publishedleast published
Citations4.0kbottom 29% of dept.154th of 216
this lab
most citedleast cited
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