Binghamton University · PsychologyBishop Neuroplasticity Lab
Christopher R Bishop · Vestal, New York
Research Focus
Dr. Christopher Bishop's lab investigates how the brain changes in response to treatment for Parkinson's disease, specifically looking at the negative side effects of the main medication used for the condition. They explore the role of serotonin neurons in the development of involuntary movements caused by the medication, aiming to better understand these processes in order to improve future treatments and enhance the quality of life for patients. The research combines both animal studies and human tissue analysis to uncover new insights into brain function and disease.
Parkinson's DiseaseL-DOPAserotonindyskinesianeuroplasticitybrain circuitschemogeneticsanimal modelsfunctional reorganizationtreatment strategies
Research Aims
3AIM 01Define how L-DOPA treatment changes serotonin pathways in Parkinson's disease.
AIM 02Investigate the effects of specific serotonin neuron activity on L-DOPA's effectiveness and side effects.
AIM 03Identify mechanisms to prevent dyskinesia and protect against adverse brain changes during treatment.
Skills the Lab Values
microscopyanimal modelselectrophysiologychemogeneticsmicrodialysisdata analysisneurotransmitter releasebehavioral assessmentserotonin pathway analysispreclinical research techniques
Output against the department
Publications129bottom 43% of dept.170th of 296
this lab
most publishedleast published
Citations4.0kbottom 37% of dept.186th of 296
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.