University of California-Los Angeles · NeuroscienceNeurodegeneration and CNS Repair Lab
Rhonda R Voskuhl · Los Angeles, California
Research Focus
Dr. Rhonda Voskuhl's lab focuses on understanding the differences in neurodegeneration in multiple sclerosis (MS) based on individual patient characteristics like sex, age, and specific disabilities. Their research aims to develop targeted treatments that repair disabilities resulting from MS by studying how various cell types in the central nervous system behave in different regions of the brain. By utilizing a range of experimental techniques, the lab assesses how these factors contribute to MS progression and therapeutic outcomes.
multiple sclerosisneurodegenerationsex differencesage effectsCNS repair
Research Aims
5AIM 01Identify distinct neurodegenerative targets for disabilities in MS.
AIM 02Investigate sex and age impacts on neurodegeneration.
AIM 03Analyze cell-specific gene expression changes in the CNS.
AIM 04Develop targeted therapies to reverse disability phenotypes in MS models.
AIM 05Characterize pathophysiological differences in regions affected by MS.
Skills the Lab Values
RNA sequencingin vivo MRIimmunohistochemistryconditional knockoutcell culturedata analysis
Output against the department
Publications152top 48% of dept.325th of 671
this lab
most publishedleast published
Citations12ktop 34% of dept.225th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.