George Washington University · EngineeringThe Myocardial Lab
Lijie Grace Zhang · Washington, District of Columbia
Research Focus
Dr. Lijie Grace Zhang's lab focuses on developing innovative engineering solutions to address challenges in cardiac tissue repair, particularly after heart attacks. They create advanced 3D bioprinting technologies to engineer functional myocardial tissue that can mimic the heart's natural structure and function. This research aims to improve treatment options for patients suffering from heart failure and enhance our understanding of cardiac regeneration.
3D bioprintingmyocardial tissuecardiovascular diseasebiomechanicstissue engineeringstem cell technologybiomanufacturingcardiac repairvascularization
Research Aims
3AIM 01Fabricate anisotropic myocardial constructs with geometric vasculature using dual 3D bioprinting.
AIM 02Investigate hemodynamic behaviors and cell responses in the vascularized myocardial construct under rhythmic mechanical stimulation.
AIM 03Evaluate the functionality of the engineered myocardial tissue in an in vivo pig myocardial infarction model.
Skills the Lab Values
3D bioprintingcell culturehydrogel fabricationmechanical stimulation techniquesanimal modelsimmunohistochemistrybiomechanical assessmentmicrocirculation analysisdata modeling
Output against the department
Publications228top 41% of dept.113th of 278
this lab
most publishedleast published
Citations13ktop 29% of dept.81st of 278
this lab
most citedleast cited
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