Johns Hopkins University · BiologyCell Motility and Signaling Lab
Peter N Devreotes · Baltimore, Maryland
Research Focus
Dr. Peter Devreotes' lab at Johns Hopkins University studies how cells move and change shape in response to their environment, which is important for both healthy and diseased conditions such as cancer. The research focuses on how cells coordinate their internal signals and structures to migrate effectively, exploring the molecular interactions that control this motility. By investigating these mechanisms, the lab aims to uncover new therapeutic strategies for diseases where cell movement goes awry.
cell migrationexcitable networkssignal transductioncancer metastasiscell morphologyactin cytoskeletonimmunologyzebrafish modelsoptogenetics
Research Aims
5AIM 01Investigate the molecular basis of cell motility and symmetry breaking.
AIM 02Analyze coordinated self-organizing signal transduction in cell migration.
AIM 03Explore the relationship between cell metabolism and signaling architecture.
AIM 04Test predictions of excitable network theory in in vivo models.
AIM 05Develop therapeutic strategies targeting dysfunctional cell migration.
Skills the Lab Values
cell culturemicroscopyoptogeneticscomputational modelingbiochemical assaysfluorescence microscopyadvanced biosensorsin vivo imaginggenetic engineering of cell lines
Output against the department
Publications346top 14% of dept.149th of 1,033
this lab
most publishedleast published
Citations27ktop 14% of dept.140th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.