Michigan State University · PhysiologyGut Motility Research Lab
Brian D. Gulbransen · East Lansing, Michigan
Research Focus
Dr. Brian D. Gulbransen's lab at Michigan State University studies how certain cells in the gut, called enteric glia, influence the way our intestines move. They focus on understanding how inflammation can change the way these glial cells and nerve cells interact, which may lead to problems like irritable bowel syndrome. Their research aims to provide new insights that can help develop better treatments for gut motility disorders.
enteric gliagut motilityneuroinflammationirritable bowel syndromeinflammatory bowel disease
Research Aims
4AIM 01Define how enteric glia interaction with neurons regulates gut motility.
AIM 02Examine how inflammation alters gliotransmission affecting neural circuits.
AIM 03Investigate the role of enteric glia in coordinating excitatory neuron activity.
AIM 04Study the impact of enteric glial regulation on colonic motor functions after inflammation.
Skills the Lab Values
cellular imagingcalcium imagingchemogeneticsmouse modelsgenetically encoded calcium indicatorsneuron-glia interactionsexperimental designdata analysis
Output against the department
Publications137bottom 45% of dept.158th of 286
this lab
most publishedleast published
Citations4.5kbottom 38% of dept.178th of 286
this lab
most citedleast cited
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