University of Pittsburgh-Pittsburgh Campus · Biomedical EngineeringThe Lung Insight Lab
Sina Tavakoli · Pittsburgh, Pennsylvania
Research Focus
Dr. Sina Tavakoli's lab focuses on improving the diagnosis and treatment of lung diseases, especially those related to inflammation and fibrosis. The lab is exploring innovative imaging techniques to assess immune responses in the lungs, particularly looking at a specific protein (CMKLR1) that is crucial in these diseases. By developing new molecular imaging tools, the lab aims to offer better precision in tracking disease progression and responses to treatments, ultimately enhancing patient care.
Lung diseasesInflammationFibrosisMolecular imagingPrecision medicineMonocyte-derived macrophagesChemokine receptorsPET imagingCOVID-19Acute lung injury
Research Aims
3AIM 01Determine the immunoprofile of CMKLR1-expressing cells in lung disease models and patient samples.
AIM 02Validate CMKLR1-targeted PET as an imaging biomarker for lung inflammation.
AIM 03Assess the prognostic ability of CMKLR1-targeted PET for disease progression and treatment response.
Skills the Lab Values
PET imagingFlow cytometryMouse modelsHistologyBiomarker validationImmunoprofilingRadiochemistryData analysisTissue processingMolecular biology techniques
Output against the department
Publications111bottom 21% of dept.467th of 595
this lab
most publishedleast published
Citations1.7kbottom 11% of dept.528th of 595
this lab
most citedleast cited
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