Johns Hopkins University · GeneticsGenome Editing and Rare Diseases Unit
Gregory A. Newby · Baltimore, Maryland
Research Focus
Dr. Gregory A. Newby’s lab at Johns Hopkins University focuses on developing advanced genome editing techniques to treat rare genetic diseases. Their research aims to create versatile tools that can address a wide range of rare genetic variants, making treatment options more accessible for patients. By improving the delivery methods of these genome editing therapies, the lab hopes to enhance their safety and effectiveness.
genome editingrare diseasesbase editingprime editingAAV vectors
Research Aims
4AIM 01Develop generalizable genome editing strategies for rare disease variants.
AIM 02Establish safer delivery systems using adeno-associated viral vectors.
AIM 03Optimize methods for treating loss-of-function and gain-of-function alleles.
AIM 04Study the application of genome editing in specific genetic disorders like Marfan Syndrome and Charcot-Marie-Tooth Disease.
Skills the Lab Values
gene editing techniquesadeno-associated viral (AAV) vector deliverymouse modelsmolecular cloningcell culture
Output against the department
Publications115bottom 37% of dept.163rd of 259
this lab
most publishedleast published
Citations15ktop 37% of dept.96th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.