The University of Texas Medical Branch at Galveston · Microbiology & ImmunologyWang Lab
Tian Wang · Galveston, Texas
Research Focus
Dr. Tian Wang's lab focuses on developing innovative vaccines to combat COVID-19, particularly using a novel approach involving porous silicon microparticles. They aim to enhance both systemic and mucosal immunity against SARS-CoV-2 variants, making vaccination more effective through different delivery methods. The research holds potential for long-term protection against viral infections and improving public health responses to pandemics.
SARS-CoV-2vaccine developmentimmunologymucosal immunityCOVID-19porous siliconsubunit vaccinesviral variants
Research Aims
3AIM 01Optimize the immunogenicity and safety of modified porous silicon microparticle-based subunit vaccines in mice.
AIM 02Investigate the protective efficacy of the vaccine against SARS-CoV-2 variants in different age groups of mice.
AIM 03Validate the vaccine's immunogenicity in hamsters and assess its effectiveness in preventing virus transmission.
Skills the Lab Values
PCRmouse modelsmucosal immunizationantigen formulationcell cultureflow cytometryWestern blotimmunization strategiesRNA sequencing
Output against the department
Publications489top 6% of dept.27th of 486
this lab
most publishedleast published
Citations10ktop 37% of dept.178th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.