Washington University in St Louis · Biomedical EngineeringCervical Cancer Precision Medicine Lab
Jin Zhang · Saint Louis, Missouri
Research Focus
Dr. Jin Zhang's lab at Washington University focuses on improving treatment outcomes for cervical cancer patients by developing predictive biomarkers and understanding the biology behind treatment resistance. Their research combines genomics and imaging techniques to identify patients at risk of treatment failure and to detect cancer recurrence early using advanced analytical methods. By integrating multi-omics data, the lab aims to personalize cancer therapy and enhance patient care.
cervical cancerradiation therapybiomarkersHPV genomicsmulti-omicsdeep learningtumor recurrencepersonalized treatmentradiogenomicsclonal evolution
Research Aims
5AIM 01Identify pre-treatment biomarkers for cervical cancer related to HPV genomic structures and patient outcomes.
AIM 02Develop post-treatment biomarkers using circulating tumor DNA for early detection of cancer recurrence.
AIM 03Integrate multi-omics data to stratify patients based on treatment resistance mechanisms.
AIM 04Use deep learning models to predict treatment response from clinical imaging data.
AIM 05Validate novel therapeutic targets through experimental assays in patient samples.
Skills the Lab Values
DNA sequencingRNA sequencingPCRWestern blotflow cytometrycell cultureimage analysisbioinformaticsmachine learningclonogenic survival assays
Output against the department
Publications338top 27% of dept.159th of 595
this lab
most publishedleast published
Citations7.0ktop 47% of dept.281st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.