Barbier Antibody Lab
Mariette Barbier · Morgantown, West Virginia
West Virginia University · Microbiology & Immunology
Research focus
Dr. Mariette Barbier's lab at West Virginia University focuses on developing new therapeutic antibodies to combat infections caused by Pseudomonas aeruginosa, especially those that are resistant to multiple drugs. They are working on a unique antibody cocktail that targets a specific component of the bacterial cell wall called lipopolysaccharide, with the hope of improving treatment options for hard-to-treat infections. Through their research, they aim to better understand how these antibodies work and provide essential data to support innovative therapies for patients.
Pseudomonas aeruginosaantibody therapymultidrug resistancesepsislipopolysaccharidebacterial infectionstherapeutic antibodies
Research aims
4AIM 01Develop therapeutic antibodies to treat MDR Pseudomonas aeruginosa infections
AIM 02Characterize the mechanism of action of the S3D4 antibody
AIM 03Evaluate the efficacy of a multivalent antibody cocktail against MDR strains
AIM 04Investigate the impact of host and bacterial factors on antibody function
Skills the lab values
antibody productionin vitro assaysanimal modelscell cultureimmunofluorescenceserotypingbiofilm analysisflow cytometry
Output against the department
121publicationsbottom 46% of the department262nd of 486
most publishedleast published
1.8kcitationsbottom 11% of the department433rd of 486
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. Position on each rail is this lab's rank, not its distance from the top: a department runs from one paper to tens of thousands, so rank is the only comparison that stays readable across it.