The University of Texas at Austin · NeuroscienceNeuroimmune Alcohol Research Lab
R. Dayne Mayfield · Austin, Texas
Research Focus
Dr. R. Dayne Mayfield's lab at the University of Texas at Austin studies how the immune system in the brain influences alcohol consumption and alcohol use disorders. They use advanced techniques to explore how changes in brain cells contribute to excessive drinking behavior and aim to identify new genetic targets for treatment. Their research combines findings from human studies and rodent models to better understand the role of neuroimmune signaling in these processes.
alcohol use disorderneuroimmune signalingsingle cell transcriptomicsmulti-omicsbrain cell biology
Research Aims
4AIM 01Investigate the effects of neuroimmune signaling on alcohol consumption.
AIM 02Identify molecular mechanisms in different brain cell types that influence drinking behavior.
AIM 03Explore genetic changes associated with alcohol dependence in human and rodent models.
AIM 04Develop new therapeutic targets based on identified gene candidates.
Skills the Lab Values
single-cell RNA sequencingspatial transcriptomicsanimal modelsgene expression analysisbioinformatics
Output against the department
Publications133bottom 47% of dept.356th of 671
this lab
most publishedleast published
Citations5.4kbottom 39% of dept.412th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.