University of Wyoming · BiochemistryCellular Transport and Development Lab
David S Fay · Laramie, Wyoming
Research Focus
Dr. David S. Fay's lab at the University of Wyoming focuses on understanding how cells transport materials and how this affects their development and the surrounding structures they rely on. Using the tiny worm C. elegans as a model, the lab investigates how specific proteins regulate the movement of lipids and proteins within cells, which is crucial for building healthy tissues. The research aims to uncover the links between cellular transport, development, and various diseases, including cancer and neurological disorders.
C. elegansmembrane traffickingextracellular matrixcell fusiondevelopmental biologylipid transportgeneticscell biologyciliopathies
Research Aims
4AIM 01Investigate how NEKL proteins affect membrane trafficking and actin dynamics.
AIM 02Examine the role of SYM proteins in lipid transport at membrane contact sites.
AIM 03Explore how cell fusion influences nuclear functions and tissue differentiation in C. elegans.
AIM 04Understand the impact of membrane-associated proteins on the structure of the extracellular matrix.
Skills the Lab Values
molecular geneticsC. elegans manipulationcell cultureproteomicsRNA sequencingsingle molecule FISH (smFISH)biochemical assaystranscriptional reporter analysisactin dynamics study
Output against the department
Publications162bottom 46% of dept.216th of 402
this lab
most publishedleast published
Citations3.3kbottom 16% of dept.338th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.