UWMUniversity of Wisconsin-Madison · Chemistry
Wang Peptide Lab
Tina Wang · Madison, Wisconsin
Research Focus
Tina Wang's research lab at the University of Wisconsin-Madison focuses on discovering new cyclic peptides, which are small protein-like molecules with potential therapeutic uses. By developing innovative methods to select cyclic peptides that function effectively within living cells, her lab aims to overcome limitations of traditional peptide discovery techniques. This work could lead to new treatments for diseases that have historically been difficult to target with drugs.
cyclic peptidesdrug discoveryprotein-protein interactionsphage displaytherapeuticscellular selectionlibrariesin vivomutation
Research Aims
5AIM 01Develop a new platform for cyclic peptide selection.
AIM 02Improve the diversity of cyclic peptides identified through in vivo methods.
AIM 03Create activity-based selections for inhibitors of protein aggregation.
AIM 04Enhance selection methods to reduce false positives in peptide discovery.
AIM 05Incorporate non-canonical amino acids into cyclic peptides to improve their properties.
Skills the Lab Values
phage displaycell cultureprotein purificationlibrary constructionmutation techniquesactivity-based selectionbioinformaticstherapeutic developmenthigh-throughput screening
Output against the department
Publications106bottom 22% of dept.168th of 216
this lab
most publishedleast published
Citations4.0kbottom 29% of dept.153rd of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.