Duke University · Biomedical EngineeringGutGuard Initiative
Ophelia Venturelli · Durham, North Carolina
Research Focus
Ophelia Venturelli's lab at Duke University focuses on how dietary fibers influence the gut microbiome and the colonization of multi-drug resistant organisms (MDROs) in humans. Through innovative methods including human studies and computational modeling, the research aims to uncover the mechanisms by which diet affects microbial dynamics and health. Ultimately, the lab seeks to develop strategies that can reduce MDRO infections.
dietary fibersgut microbiomemulti-drug resistant organismsmicrobe interactionshealth interventions
Research Aims
5AIM 01Elucidate the relationship between diet and human gut microbiome taxa.
AIM 02Develop computational models to understand microbe interactions within the gut.
AIM 03Identify dietary fibers that influence multi-drug resistant organism fitness.
AIM 04Design effective dietary strategies to reduce MDRO colonization in the gut.
AIM 05Test bacterial combinations in a mouse model to evaluate their impact on MDRO decolonization.
Skills the Lab Values
DNA sequencingcomputational modelinghigh-throughput culturinggerm-free mouse experimentsmachine learninglongitudinal study designmicrobiome analysisdata-driven modelingsystems biology
Output against the department
Publications89bottom 14% of dept.511th of 595
this lab
most publishedleast published
Citations3.2kbottom 24% of dept.450th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.