University of Arkansas for Medical Sciences · BiologyDrew Myelination Lab
Paul D Drew · Little Rock, Arkansas
Research Focus
Dr. Paul D. Drew's lab focuses on understanding how fetal alcohol exposure affects brain development, particularly through the impact on oligodendrocyte-lineage cells that are essential for myelination in the central nervous system. The research aims to uncover the mechanisms of neurological deficits associated with Fetal Alcohol Spectrum Disorders (FASD), with hopes of finding therapeutic approaches for prevention and treatment. By utilizing rodent models, the lab explores the interactions between oligodendrocyte cells and neurons and seeks potential strategies to enhance myelination in affected brains.
Fetal Alcohol Spectrum Disordersoligodendrocytesneurological deficitsmyelinationethanol exposure
Research Aims
3AIM 01Determine the effects of ethanol on oligodendrocyte lineage cells.
AIM 02Examine OPC-neuron interactions and OPC motility affected by alcohol exposure.
AIM 03Investigate protective agents that promote myelination against ethanol-induced damage.
Skills the Lab Values
immunohistochemistryRNA sequencinglight microscopytwo-photon imagingmouse modelscell culturebehavioral testinglineage fate mappingdata analysis
Output against the department
Publications86bottom 28% of dept.745th of 1,033
this lab
most publishedleast published
Citations4.7kbottom 36% of dept.659th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.