Texas A&M University-College Station · Microbiology & ImmunologyTuberculosis Vaccine Research Lab
Jeffrey D. Cirillo · College Station, Texas
Research Focus
Dr. Jeffrey D. Cirillo's lab at Texas A&M University specializes in understanding tuberculosis (TB) and improving vaccines against this disease. They study the BCG vaccine's variability in effectiveness and develop advanced imaging techniques to detect Mycobacterium tuberculosis in real-time. Through animal models and human studies, they aim to correlate immune responses with vaccine efficacy and create innovative ways to monitor TB infections and assess new treatments more quickly.
tuberculosisBCG vaccineMycobacterium tuberculosisvaccine efficacyimaging technologiesepigeneticsimmune responseanimal modelstherapeuticsinfection detection
Research Aims
5AIM 01Investigate differences in immune response to BCG vaccine substrains in human and animal models.
AIM 02Develop novel imaging technologies for rapid detection of Mycobacterium tuberculosis.
AIM 03Assess the efficacy of BCG vaccination by analyzing protective biosignatures.
AIM 04Explore the mechanisms underlying epigenetic changes in antigen-presenting cells due to BCG.
AIM 05Validate imaging techniques to monitor TB infection in real-time across various tissues.
Skills the Lab Values
PCRanimal modelsflow cytometryscRNA-seqimaging technologymicroendoscopyimmunology techniquescell culturegenetic analysisdata analysis
Output against the department
Publications174top 38% of dept.184th of 486
this lab
most publishedleast published
Citations7.0kbottom 49% of dept.246th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.