University of California-Berkeley · EngineeringPoint-of-Care Diagnostics Lab
Jun-Chau Chien · Berkeley, California
Research Focus
Dr. Jun-Chau Chien's research lab focuses on developing innovative point-of-care (POC) diagnostic systems that can rapidly detect biomarkers directly at the site of patient care. By integrating miniaturized technology and advanced molecular sensing techniques, the lab aims to create portable devices that can analyze unprocessed samples like urine. This research holds particular significance for resource-limited settings, especially in improving maternal health outcomes through early detection of conditions like preeclampsia.
point-of-care diagnosticsbiosensingCMOS technologyaptamer switchesbioelectronics
Research Aims
4AIM 01Develop a miniaturized CMOS chip for biosensing applications.
AIM 02Screen and optimize aptamers for specific biomarker detection.
AIM 03Integrate advanced electrodes into the detection system.
AIM 04Validate the system's performance with real urine samples.
Skills the Lab Values
microfluidicselectrochemical analysisCMOS fabricationaptamer selectionwireless communications
Output against the department
Publications95bottom 20% of dept.222nd of 278
this lab
most publishedleast published
Citations2.0kbottom 14% of dept.238th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.