Stanford University · BiologyLu Lab
Bingwei Lu · Stanford, California
Research Focus
Dr. Bingwei Lu's lab at Stanford University explores the connections between tau protein abnormalities and mitochondrial dysfunction in neurodegenerative diseases like Alzheimer's and Parkinson's. By understanding how these factors interact, the lab aims to develop new therapeutic strategies to combat a variety of brain disorders. The research combines molecular genetics, biochemistry, and cell biology techniques to uncover the mechanisms underlying these diseases.
Tau proteinMitochondrial dysfunctionNeurodegenerative diseasesAlzheimer's diseaseParkinson's diseaseProteostasisMolecular geneticsCell cultureBiochemistry
Research Aims
5AIM 01Investigate how tau protein interacts with mitochondrial proteins
AIM 02Determine the role of mitochondrial dysfunction in neurodegenerative disease progression
AIM 03Explore the link between mitochondrial health and protein homeostasis
AIM 04Test therapeutic approaches targeting tau and mitochondrial pathways
AIM 05Utilize animal and iPSC-derived cell models to study disease mechanisms
Skills the Lab Values
Animal modelsCell culture techniquesMolecular cloningBiochemical assaysGenomic sequencingCRISPR techniquesImmunostainingMicroscopyRNA interference
Output against the department
Publications123bottom 44% of dept.577th of 1,033
this lab
most publishedleast published
Citations10ktop 36% of dept.373rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.