The University of Texas at Austin · PharmacologyManganese Neurotoxicity Research Unit
Somshuvra Mukhopadhyay · Austin, Texas
Research Focus
Dr. Somshuvra Mukhopadhyay's lab at the University of Texas at Austin focuses on understanding how manganese, an essential metal, can become toxic and lead to neurological diseases. The lab studies the mechanisms of manganese excretion and how it affects neurotoxicity, particularly in vulnerable populations like children. By exploring the relationship between manganese levels in the body and neurological health, the lab aims to find new therapeutic strategies for manganese-related disorders.
manganese neurotoxicityexcretion mechanismsneurodegenerative diseasesenvironmental exposuremotor function impairmentdopaminergic neuronsearly-life exposuretherapeutic strategies
Research Aims
3AIM 01Investigate the role of manganese excretion in neurotoxic effects in the brain.
AIM 02Determine if increasing manganese excretion can protect against neurotoxicity.
AIM 03Explore the impact of early-life manganese exposure on dopaminergic neurons and motor function.
Skills the Lab Values
mouse modelsgenetic engineeringbehavioral assaysbiochemical assaysneuroscience microscopymolecular biology techniquesPCRWestern blottingflow cytometry
Output against the department
Publications70bottom 14% of dept.396th of 462
this lab
most publishedleast published
Citations3.2kbottom 25% of dept.348th of 462
this lab
most citedleast cited
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