Duke University · Mathematics & StatisticsCenter for Real-World Data Analysis
Xiaofei Wang · Durham, North Carolina
Research Focus
Dr. Xiaofei Wang's lab focuses on enhancing clinical trials by utilizing real-world data (RWD) while addressing potential biases that could affect treatment evaluations. The lab aims to create new statistical methods and frameworks to integrate RWD effectively, ensuring that clinical trial results are robust and reliable. Additionally, they prioritize sharing these innovative approaches with industry and academic researchers to promote better regulatory practices in drug development.
clinical trialsreal-world datasensitivity analysisexternal controlsstatistical methodsbias mitigationdrug developmentregulatory decision-makingbiostatistics
Research Aims
5AIM 01Develop frameworks to assess hidden biases in clinical trial data.
AIM 02Create robust statistical methods for integrating real-world data.
AIM 03Enhance the efficiency of clinical trial comparisons using external controls.
AIM 04Facilitate collaboration through workshops and educational resources.
AIM 05Promote the use of real-world evidence in regulatory settings.
Skills the Lab Values
statistical analysissensitivity analysis framework developmentdata discrepancies adjustmentsoftware developmentclinical trial designworkshops organizationdata visualizationstatistical software proficiency (e.g., R, SAS)
Output against the department
Publications546top 11% of dept.15th of 131
this lab
most publishedleast published
Citations11ktop 34% of dept.45th of 131
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.