AECAlbert Einstein College of Medicine · Genetics
Dawlaty Lab
Meelad Dawlaty · Bronx, New York
Research Focus
Dr. Meelad Dawlaty's lab focuses on understanding how specific enzymes, known as Tet enzymes, play a crucial role in the formation of blood cells during embryonic development. They study how these enzymes help regulate the transition of cells from one type to another, specifically from endothelial cells to blood progenitor cells. By exploring the molecular mechanisms behind these processes, the lab aims to inform potential treatments for blood disorders and improve methods for generating blood cells in the lab for clinical applications.
Tet enzymesembryonic hematopoiesisblood cell formationepigeneticsstem cells
Research Aims
2AIM 01Define the role of Tet enzymes in the specification of hematopoietic cells from endothelial cells during embryonic development.
AIM 02Determine how Tet-mediated DNA demethylation activates hematopoietic gene programs in endothelial cells.
Skills the Lab Values
PCRcell culturemouse modelsflow cytometryWestern blotgene expression analysisembryonic stem cell derivationmolecular biology techniquesDNA methylation analysis
Output against the department
Publications59bottom 12% of dept.228th of 259
this lab
most publishedleast published
Citations9.3kbottom 49% of dept.133rd of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.