University of Pennsylvania · NeuroscienceNusbaum Lab
Michael P Nusbaum · Philadelphia, Pennsylvania
Research Focus
Dr. Michael P. Nusbaum's research focuses on how hormones influence specific neural circuit states. By studying the stomatogastric ganglion in crabs, his lab investigates how different hormones modulate the activity of neural circuits that control chewing and food passage. This research not only advances our understanding of hormonal effects on brain function but also sheds light on the complexities of neural circuits in various behavioral states.
hormonal modulationneural circuitselectrophysiologyCancer borealisstomatogastric ganglionneuromodulationsynaptic mechanismsbehavioral states
Research Aims
5AIM 01Investigate how hormones from behavioral states influence circuit states in crabs.
AIM 02Characterize the responses of different neuronal circuits to hormone exposure.
AIM 03Identify specific hormones affecting circuit activity and their concentrations.
AIM 04Explore cellular and synaptic mechanisms behind hormonal modulation.
AIM 05Understand the impact of a complete hormonal environment on circuit state function.
Skills the Lab Values
electrophysiologymass spectrometryneural circuit analysisdata collectioncircuit neuron manipulationvoltage clamp techniquesdynamic clamp techniquesexperimental designbiochemical assaysanatomy of crab nervous system
Output against the department
Publications106bottom 36% of dept.429th of 671
this lab
most publishedleast published
Citations6.3kbottom 44% of dept.379th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.