University of Pennsylvania · Biomedical EngineeringThe Imaging Precision Lab
Elizabeth Mcdonald · Philadelphia, Pennsylvania
Research Focus
Dr. Elizabeth Mcdonald's lab at the University of Pennsylvania focuses on improving cancer treatment through innovative imaging techniques. The lab is developing a new PET imaging method that can predict how well patients with breast cancer will respond to specific therapies using PARP inhibitors. This research aims to personalize cancer treatments and reduce unnecessary side effects by matching patients with the most effective therapies based on their tumor characteristics.
PARP inhibitorsPET imagingbreast cancerprecision medicinebiomarkers
Research Aims
3AIM 01Develop a non-invasive biomarker for sensitivity to PARP inhibitors.
AIM 02Evaluate the predictive value of imaging-tissue markers in clinical settings.
AIM 03Test the hypothesis that imaging tracer uptake correlates with patient response in animal models.
Skills the Lab Values
immunohistochemistryanimal modelsradioligand binding assaycell cultureclinical trialsdata analysisbiopsy techniquesfunctional imaging
Output against the department
Publications135bottom 28% of dept.429th of 595
this lab
most publishedleast published
Citations3.6kbottom 28% of dept.427th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.