Oakland University · BiologyDelorme-Axford Lab
Elizabeth Delorme-Axford · Rochester Hills, Michigan
Research Focus
Dr. Elizabeth Delorme-Axford's lab at Oakland University explores the mechanisms of cell survival under stress conditions, particularly through a process called autophagy. They focus on understanding how specific enzymes, known as pseudouridine synthases, influence cell health by regulating this vital process. By using yeast as a model system, the lab engages undergraduate students in hands-on research that has implications for human health, including diseases like cancer and neurodegeneration.
autophagypseudouridine synthasescell survivalcell stressbiomedical researchyeast model systemmolecular genetics
Research Aims
5AIM 01Investigate how pseudouridine synthases affect autophagy.
AIM 02Understand the regulation of cell survival mechanisms during stress.
AIM 03Explore the role of autophagy in human health and disease.
AIM 04Conduct experiments using yeast to model human cellular processes.
AIM 05Engage undergraduate students in authentic research experiences.
Skills the Lab Values
cell culturemolecular geneticsbiochemical assaysRNA analysisgene expression techniquesyeast geneticsdata analysisexperimental design
Output against the department
Publications41bottom 8% of dept.946th of 1,033
this lab
most publishedleast published
Citations11ktop 35% of dept.360th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.