Yale University · BiologySuarez Cardiovascular Lab
Yajaira Suarez · New Haven, Connecticut
Research Focus
Dr. Yajaira Suarez's lab at Yale University studies how certain cellular processes in blood vessels and immune cells contribute to heart diseases, particularly atherosclerosis. They focus on understanding how non-coding RNAs and specific metabolic pathways influence the behavior of endothelial cells, smooth muscle cells, and macrophages in the context of vascular inflammation. The ultimate goal of this research is to uncover new treatment strategies for cardiovascular diseases through a better understanding of these mechanisms.
atherosclerosisvascular metabolismimmune functionnon-coding RNAscellular metabolismcardiovascular diseaseendothelial cellssmooth muscle cellsmacrophage activationinflammation
Research Aims
5AIM 01Investigate the role of non-coding RNAs in regulating cellular metabolism during atherosclerosis
AIM 02Elucidate the metabolic pathways involved in endothelial cell dysfunction
AIM 03Explore the interaction between macrophage metabolic states and their inflammatory responses
AIM 04Determine how smooth muscle cell phenotypes are affected by metabolic signaling
AIM 05Identify potential therapeutic targets based on metabolic processes in vascular diseases.
Skills the Lab Values
PCRcell cultureRNA extraction and analysisWestern blotflow cytometrymicroscopyin vivo mouse modelslipid profilingstatistical analysis in Rbioinformatics
Output against the department
Publications143top 48% of dept.490th of 1,033
this lab
most publishedleast published
Citations14ktop 26% of dept.269th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.