University of Utah · BiologyLo Immunology Lab
Wan-Lin Lo · Salt Lake City, Utah
Research Focus
Dr. Wan-Lin Lo's lab at the University of Utah focuses on understanding how CD7 signaling affects T cells, which are crucial for our immune response. The lab studies how CD7 influences T cell activation and differentiation, especially during infections and diseases like cancer and autoimmune disorders. By uncovering the roles of CD7, they aim to develop new therapies that could enhance T cell responses or prevent them from becoming exhausted during chronic conditions.
CD7T cell signalingimmunomodulationviral infectionautoimmune diseasescancerT cell differentiationimmune response
Research Aims
5AIM 01Characterize the mechanisms of CD7's role in T cell activation during infections.
AIM 02Investigate how lack of CD7 affects T cell fate during viral infection.
AIM 03Explore CD7 as a target for improving T cell responses in cancer.
AIM 04Analyze CD7 signaling's impact on T cell exhaustion and autoimmunity.
AIM 05Develop immunomodulatory strategies based on CD7 function.
Skills the Lab Values
cell cultureproteomicstranscriptomicsepigeneticsmolecular profilingflow cytometryanimal modelsimmunofluorescencedata analysis
Output against the department
Publications40bottom 8% of dept.952nd of 1,033
this lab
most publishedleast published
Citations2.3kbottom 17% of dept.861st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.