University of Virginia-Main Campus · Biomedical EngineeringDolatshahi Lab
Sepideh Dolatshahi · Charlottesville, Virginia
Research Focus
Dr. Sepideh Dolatshahi's lab at the University of Virginia focuses on understanding how antibodies are transferred from mothers to their infants through the placenta. By exploring the roles of different receptors involved in this process, the lab aims to optimize maternal vaccination strategies to provide better early-life immunity for newborns. Their work combines experimental biology with mathematical modeling to create more effective vaccines for expectant mothers.
antibody transfermaternal vaccinationplacentaFc receptorsnewborn immunityvaccine designimmunologytransplacental transfermathematical modeling
Research Aims
3AIM 01Identify key Fc receptors involved in antibody transfer through the placenta.
AIM 02Determine the best antibody characteristics that aid in transfer efficiency.
AIM 03Develop a mathematical model predicting the dynamics of antibody transfer from mother to fetus.
Skills the Lab Values
cell cultureimmunofluorescencemathematical modelingbiological assaysanimal modelsdata analysisexperimental designtissue imaging
Output against the department
Publications51bottom 6% of dept.560th of 595
this lab
most publishedleast published
Citations999bottom 6% of dept.559th of 595
this lab
most citedleast cited
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