University of Miami · NeurosciencePerez-Pinzon Lab
Miguel A Perez-Pinzon · Coral Gables, Florida
Research Focus
Dr. Miguel A Perez-Pinzon's lab at the University of Miami focuses on understanding how ischemic preconditioning can protect the brain from stroke-related damage. They study the role of specific molecules like Brain-Derived Neurotrophic Factor (BDNF) and Resveratrol in improving brain function and synaptic health. The lab aims to uncover new therapeutic strategies to help patients recover cognitive function after a stroke and potentially benefit those with related conditions like Alzheimer's disease.
ischemic preconditioningcerebral ischemiacognitive functionBDNFstroke recoverysynaptic plasticityresveratrolepigenetic modificationsanimal modelsneuroprotection
Research Aims
3AIM 01Determine the effect of resveratrol preconditioning on cognitive outcomes in both young and aged rats.
AIM 02Investigate the mechanisms through which resveratrol preconditioning improves synaptic health following middle cerebral artery occlusion.
AIM 03Identify transcriptional profiles associated with the effects of resveratrol preconditioning on hippocampal synaptic plasticity.
Skills the Lab Values
animal model techniqueselectrophysiologycell culturemolecular biology techniquesgene expression analysisdrug administration in rodentsbehavioral testing in rodentsimmunohistochemistrydata analysis using statistical softwarePCR
Output against the department
Publications248top 30% of dept.197th of 671
this lab
most publishedleast published
Citations10ktop 39% of dept.262nd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.