University of California-Los Angeles · Biomedical EngineeringSchaue Lab
Dorthe Schaue · Los Angeles, California
Research Focus
At Dr. Dorthe Schaue's lab at UCLA, researchers focus on using a new imaging technique called autofluorescence to measure how much radiation exposure organisms have experienced. This research aims to develop a way to quickly assess radiation damage, which is crucial for making timely medical decisions during emergencies. By studying how cells respond to radiation at the molecular level, the lab hopes to create a tool that can predict acute health risks related to radiation and enhance safety protocols during radiological events.
radiation exposureautofluorescencebiodosimetrybiomarkersredox biology
Research Aims
5AIM 01Develop a biodosimeter using autofluorescence to monitor radiation exposure.
AIM 02Examine dose-response relationships and time course of autofluorescence in vitro.
AIM 03Assess autofluorescence in vivo using non-invasive imaging techniques.
AIM 04Align autofluorescence responses with intrinsic radiosensitivity in different mouse strains.
AIM 05Investigate the relationship between redox processes and radiation-induced autofluorescence.
Skills the Lab Values
autofluorescence imagingcell cultureflow cytometrytissue sample analysismouse models
Output against the department
Publications111bottom 21% of dept.465th of 595
this lab
most publishedleast published
Citations5.2kbottom 40% of dept.359th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.