Oregon Health & Science University · Biomedical EngineeringBarajas Lab
Ramon Francisco Barajas · Portland, Oregon
Research Focus
Dr. Ramon Francisco Barajas's research lab at Oregon Health & Science University focuses on advanced imaging techniques to improve treatments for glioblastoma, a particularly aggressive brain cancer. The lab investigates the role of the hypoxic tumor immune microenvironment, specifically how certain immune cells can suppress the effectiveness of cancer therapies. By better understanding this immune response, the lab aims to correlate imaging findings with treatment outcomes, ultimately contributing to more effective immunotherapy strategies for cancer patients.
glioblastomahypoxiatumor microenvironmentimmunotherapyimmune modulationPET/MRItumor-associated macrophagesnanoimagingneuroinflammationcancer therapy
Research Aims
5AIM 01Quantify the immunosuppressive hypoxic tumor immune microenvironment in glioblastoma patients using novel imaging techniques.
AIM 02Assess how therapeutic modulation of tumor-associated macrophages affects treatment outcomes in glioblastoma.
AIM 03Develop a biologically specific imaging measure for the hypoxic tumor immune microenvironment.
AIM 04Evaluate the efficacy of new immunotherapeutic strategies based on the tumor immune microenvironment assessments.
AIM 05Test the impact of the hypoxic tumor microenvironment on treatment sensitivity in glioblastoma models.
Skills the Lab Values
PET imagingMRI technologycell culturemouse modelsxenograftsnanoparticle synthesisimmunohistochemistrybiological validationclinical trial methodologydata analysis in clinical research
Output against the department
Publications114bottom 22% of dept.463rd of 595
this lab
most publishedleast published
Citations3.5kbottom 27% of dept.436th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.