University of Missouri-Columbia · BiologyPicking Lab
Wendy L. Picking · Columbia, Missouri
Research Focus
Dr. Wendy L. Picking's research lab focuses on developing vaccines to prevent infections caused by the antibiotic-resistant bacterium Pseudomonas aeruginosa. The lab explores innovative vaccine formulations that can stimulate an immune response to provide protection against this opportunistic pathogen, particularly in vulnerable populations like the elderly and patients with chronic conditions. By utilizing animal models, the lab assesses the effectiveness of these vaccines to ultimately enhance public health outcomes.
Pseudomonas aeruginosavaccine developmentantibiotic resistancetype III secretion systemimmune responserodent modelspublic healthimmunologypathogenesisprevention strategies
Research Aims
5AIM 01Develop a vaccine to prevent infections by Pseudomonas aeruginosa.
AIM 02Assess vaccine efficacy in rodent models.
AIM 03Investigate the immune response generated by the vaccine.
AIM 04Explore the use of novel adjuvants to enhance vaccine effectiveness.
AIM 05Determine the protective capability of combined vaccine antigens against multiple Pa strains.
Skills the Lab Values
PCRcell cultureanimal handlingimmunization techniquesserum analysisflow cytometryvaccination protocolsrodent model experimentationmolecular cloningprotein purification
Output against the department
Publications118bottom 42% of dept.592nd of 1,033
this lab
most publishedleast published
Citations4.3kbottom 33% of dept.696th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.