University of Michigan-Ann Arbor · BiologyFood Allergy Research Lab
Simon Patrick Hogan · Ann Arbor, Michigan
Research Focus
Dr. Simon Patrick Hogan's lab focuses on understanding food allergies, particularly in children, and aims to find new ways to treat them. The lab studies how certain immune cells in the gastrointestinal tract interact with food antigens and how this may lead to allergic reactions. By investigating the roles of specific signaling pathways and cell types, the team seeks to uncover new therapeutic targets that could improve treatments for food allergies.
food allergyIL-9gastrointestinal mast cellsimmune mechanismsgoblet cells
Research Aims
3AIM 01Investigate the role of IL-9 in gastrointestinal mast cell density and food allergy susceptibility.
AIM 02Identify the signals promoting IL-9 production in immune cells.
AIM 03Explore how goblet cells facilitate the passage of dietary antigens and trigger allergic responses.
Skills the Lab Values
cell culturemouse modelsimmunofluorescencebiopsy analysisflow cytometryRNA sequencingPCRdata analysisprotein assays
Output against the department
Publications289top 20% of dept.205th of 1,033
this lab
most publishedleast published
Citations18ktop 21% of dept.221st of 1,033
this lab
most citedleast cited
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