University of California-San Francisco · Biomedical EngineeringRaleigh Tumor Lab
David R Raleigh · San Francisco, California
Research Focus
Dr. David Raleigh's lab at UCSF focuses on understanding and treating meningiomas, a type of brain tumor. The lab studies the genetic mechanisms that cause these tumors and aims to develop better treatments using innovative models. By using human samples and advanced techniques like organoids and CRISPR, they hope to improve outcomes for patients with meningiomas.
meningiomacell cycleCDK6organoid modelsCRISPRtumor biologycancer therapeuticspreclinical modelsbiomarkersclinical trials
Research Aims
5AIM 01Understand the genetic mechanisms causing meningioma growth.
AIM 02Develop and test CDK6 inhibitors on meningiomas.
AIM 03Establish preclinical models for meningioma research.
AIM 04Identify biomarkers for response to meningioma treatments.
AIM 05Integrate innovative experimental approaches to improve meningioma therapeutics.
Skills the Lab Values
CRISPR interferencemolecular profilingpatient derived xenograftsorganoid developmentcell culturedrug kineticsbiochemical assaysflow cytometryhistologyDNA methylation profiling
Output against the department
Publications516top 15% of dept.90th of 595
this lab
most publishedleast published
Citations11ktop 30% of dept.181st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.