Upstate Medical University · Microbiology & ImmunologyDengue Immunology Research Lab
Adam T Waickman · Syracuse, New York
Research Focus
Dr. Adam T. Waickman's lab focuses on understanding how dengue virus infection interacts with the immune system, particularly through a mechanism called B-cell receptor dependent enhancement (BDE). They investigate why some individuals experience severe symptoms while others remain asymptomatic after infection. Their research aims to reveal how B cells, typically involved in immune protection, can also contribute to the risk of severe dengue outcomes.
dengue virusB cell receptorimmune responsepathogenesisantibody-dependent enhancement
Research Aims
4AIM 01Investigate how B cell receptors mediate dengue virus infection.
AIM 02Determine the role of pre-existing antibodies in dengue pathogenesis.
AIM 03Explore the immune response dynamics during dengue infection.
AIM 04Identify risk factors that influence severe dengue outcomes.
Skills the Lab Values
cell culturefluorescence microscopyflow cytometryanimal modelsimmunological assays
Output against the department
Publications115bottom 43% of dept.274th of 486
this lab
most publishedleast published
Citations4.1kbottom 31% of dept.337th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.