Johns Hopkins University · NeuroscienceLeigh Cognition Lab
Richard Leigh · Baltimore, Maryland
Research Focus
Dr. Richard Leigh's lab at Johns Hopkins University focuses on understanding cognitive decline after strokes. They investigate how damage to the blood-brain barrier may contribute to memory problems and brain changes in stroke survivors. By studying brain imaging and developing new diagnostic methods, the lab aims to identify patients at risk for dementia and improve treatment strategies.
blood-brain barrierpost-stroke cognitive declinevascular dementiawhite matter hyperintensitiesbrain imagingMRIAlzheimer's diseasebiomarkers
Research Aims
3AIM 01Investigate how blood-brain barrier disruption relates to cognitive decline after a stroke.
AIM 02Evaluate the progression of white matter changes in stroke patients using MRI.
AIM 03Develop a new MRI method for measuring blood-brain barrier permeability without contrast agents.
Skills the Lab Values
magnetic resonance imaging (MRI)arterial spin labeling (ASL)cognitive testingbiomarker developmentdata collection in clinical settings
Output against the department
Publications414top 15% of dept.99th of 671
this lab
most publishedleast published
Citations16ktop 26% of dept.173rd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.