George Washington University · Microbiology & ImmunologyNeuroimmune Pain Research Lab
Aakanksha Jain · Washington, District of Columbia
Research Focus
Dr. Aakanksha Jain's lab focuses on understanding how the nervous system and immune system interact to influence pain and inflammation in autoimmune arthritis, particularly rheumatoid arthritis. The lab's research aims to uncover the underlying mechanisms of joint inflammation and pain, which could lead to new therapeutic approaches for managing this debilitating condition. Students will be involved in cutting-edge research that combines neuroscience and immunology, utilizing advanced techniques to explore these critical interactions.
neuroimmune interactionsrheumatoid arthritispain mechanismsautoimmune disordersinflammationnociceptorsimmune cell functionmachine learningtherapeutic development
Research Aims
5AIM 01Map neuroimmune receptor-ligand interactions in joints to identify pathways linked to arthritis.
AIM 02Determine how sensory neurons respond to immune signals during rheumatoid arthritis.
AIM 03Analyze pain behaviors in mice to link neural and immune function.
AIM 04Investigate the role of nociceptors in modulating immune responses during inflammation.
AIM 05Develop novel therapeutic strategies targeting neuroimmune interactions to alleviate arthritis pain.
Skills the Lab Values
single-cell analysisanimal models of arthritispain behavior assessmentreceptor-ligand mappingneuroscience techniquesimmunological assaysdata analysis using Pythoninnovative imaging techniquesmachine learning applications in biology
Output against the department
Publications31bottom 5% of dept.460th of 486
this lab
most publishedleast published
Citations1.5kbottom 9% of dept.443rd of 486
this lab
most citedleast cited
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