University of Maryland-College Park · BiologyShi Lab
Meiqing Shi · College Park, Maryland
Research Focus
Dr. Meiqing Shi's lab at the University of Maryland focuses on understanding how the immune system responds to infections caused by Cryptococcus neoformans, particularly in HIV/AIDS patients. They study a severe condition known as immune reconstitution inflammatory syndrome (IRIS) that can develop when patients undergo antiretroviral therapy. By using animal models, the lab aims to identify specific immune cell types and cytokines involved in this dangerous inflammatory response, which could lead to new treatments for affected patients.
cryptococcal IRISHIV/AIDSinflammatory responseimmune reconstitutionCryptococcus neoformans
Research Aims
3AIM 01Identify the leukocyte subsets that contribute to lethal cryptococcal IRIS.
AIM 02Determine the cytokines involved in fatal inflammatory responses during cryptococcal IRIS.
AIM 03Investigate the regulatory factors affecting CD4+ T cell responses during cryptococcal IRIS.
Skills the Lab Values
mouse modelscell cultureflow cytometrycytokine assaysimmunohistochemistry
Output against the department
Publications133bottom 47% of dept.539th of 1,033
this lab
most publishedleast published
Citations4.0kbottom 30% of dept.721st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.