University of Pennsylvania · Biomedical EngineeringLiver Cancer Diagnostic Lab
Terence P Gade · Philadelphia, Pennsylvania
Research Focus
Dr. Terence Gade's lab at the University of Pennsylvania focuses on improving diagnosis and treatment of liver cancer, particularly hepatocellular carcinoma (HCC). They work on developing advanced imaging techniques and patient-derived models to better understand tumor behavior and predict treatment responses. This research aims to enhance patient outcomes by creating more effective therapies based on personalized data from these models.
hepatocellular carcinomapatient-derived xenograftsdynamic nuclear polarizationimaging techniquestreatment responsepersonalized therapypreclinical models
Research Aims
3AIM 01Validate rat models of hepatocellular carcinoma for their predictive value on treatment responses in patients.
AIM 02Establish a humanized immune system in rat models to study response to advanced therapies.
AIM 03Define characteristics of liver injury in humanized rat models that mimic chronic liver disease.
Skills the Lab Values
dynamic nuclear polarization MRIpatient-derived tumor modelsanimal modelingimmunocompromised rat modelshistological analysismetabolomicsdata curationclinical data analysisimaging biomarker analysis
Output against the department
Publications242top 42% of dept.251st of 595
this lab
most publishedleast published
Citations3.9kbottom 31% of dept.412th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.