Stanford University · PharmacologyCytoplasmic Dynamics Lab
James E. Ferrell · Stanford, California
Research Focus
Dr. James E. Ferrell's lab at Stanford University focuses on exploring the organization and function of cytoplasm in biological systems, particularly using cell-free extracts from Xenopus eggs. The research aims to uncover how cellular components self-organize, how chemical signals propagate through cells, and how these processes affect fundamental aspects of cell physiology. This work combines experimental and theoretical methods, making it a vital area of study for understanding complex biochemical processes in living organisms.
cell-free extractsXenopuscytoplasmself-organizationtrigger wavescell physiologybiochemical regulationmathematical modelingtranscription
Research Aims
4AIM 01Investigate the mechanism of self-organization in Xenopus cytoplasm.
AIM 02Examine how cytoplasmic crowding affects ATP production and utilization.
AIM 03Study the propagation of trigger waves in cellular contexts.
AIM 04Analyze the midblastula transition using reconstituted transcription in egg extracts.
Skills the Lab Values
Xenopus egg extract manipulationmathematical modelingordinary differential equationsagent-based modelingin vitro reconstitutionchemical activity wave analysisATP production measurementcell cycle studiesexperimental design
Output against the department
Publications190top 47% of dept.213th of 462
this lab
most publishedleast published
Citations22ktop 15% of dept.67th of 462
this lab
most citedleast cited
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