UCUniversity of Cincinnati-Main Campus · Pharmacology
Airway Inflammation and Fear Lab
Renu Sah · Cincinnati, Ohio
Research Focus
Dr. Renu Sah's lab at the University of Cincinnati focuses on understanding how airway inflammation, particularly from asthma, affects fear regulation and may contribute to conditions like PTSD. By studying mouse models, the lab investigates the immune and neural mechanisms at play, aiming to uncover potential therapeutic targets for treating fear-related disorders. Their research is particularly relevant for understanding how asthma and other pulmonary pathologies can influence mental health.
PTSDairway inflammationasthmaimmune mediatorsfear regulationmicroglianeural substratestransgenic mouse modelselectrophysiology
Research Aims
2AIM 01Assess how SFO-IL projections regulate fear extinction and IL neuronal activity in inflammation models.
AIM 02Evaluate the role of microglial IL-17RA signaling in driving fear extinction deficits in asthma-induced models.
Skills the Lab Values
mouse modelselectrophysiologypatch-clamp recordingsretroviral vectorsAAV transductionchemogeneticsimmunohistochemistrycell culturebehavioral assaysgene expression analysis
Output against the department
Publications108bottom 29% of dept.328th of 462
this lab
most publishedleast published
Citations2.6kbottom 18% of dept.378th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.