University of Nevada-Reno · PhysiologyThe Gastromotive Lab
Sean M Ward · Reno, Nevada
Research Focus
Dr. Sean Ward's lab at the University of Nevada Reno focuses on understanding how human stomach muscles work, specifically why some people have trouble with stomach function. They investigate the electrical signals that help the stomach move food through the digestive system and how factors like age, gender, and genetics affect these processes. By studying human tissues directly, the lab aims to uncover new insights that can lead to better treatments for conditions like gastroparesis and dyspepsia.
gastric motilityelectrophysiologyhuman stomachpacemaker cellsfunctional disorders
Research Aims
3AIM 01Characterize the morphology and molecular phenotype of gastric muscles in humans.
AIM 02Investigate mechanisms of pacemaker activity in the human stomach.
AIM 03Explore the role of specific cells in regulating gastric electrical activity.
Skills the Lab Values
intracellular microelectrode recordingssingle-nucleus RNA sequencing (snRNA-seq)calcium imagingtissue morphology analysisdata analysis in electrophysiology
Output against the department
Publications286top 18% of dept.51st of 286
this lab
most publishedleast published
Citations19ktop 16% of dept.45th of 286
this lab
most citedleast cited
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