University of Iowa · BiologyBadovinac Immunology Lab
Vladimir P Badovinac · Iowa City, Iowa
Research Focus
Dr. Vladimir Badovinac's lab at the University of Iowa focuses on understanding how radiation exposure affects the immune system, particularly memory CD8 T cells that are crucial for fighting infections. The lab aims to uncover the mechanisms behind radiation-induced immune dysfunction and identify strategies to improve the function and numbers of these important immune cells after exposure. Their research could lead to better medical countermeasures for individuals exposed to radiation, whether accidentally or intentionally.
radiation exposurememory CD8 T cellsimmune dysfunctionT cell responsesmedical countermeasures
Research Aims
4AIM 01Investigate how whole-body radiation impacts tissue-specific memory CD8 T cells.
AIM 02Evaluate targeted vaccine strategies to restore memory CD8 T cell numbers and function post-irradiation.
AIM 03Define the mechanisms of radiation-induced changes in circulating and tissue-resident memory CD8 T cells.
AIM 04Assess the effects of radiation on immune responses to viral infections.
Skills the Lab Values
immunological assayscell cultureflow cytometrymouse modelsRNA sequencingWestern blotvaccine developmentin vivo imagingbioinformatics
Output against the department
Publications212top 30% of dept.312th of 1,033
this lab
most publishedleast published
Citations11ktop 34% of dept.349th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.