Texas A&M University-College Station · BiologyThe Metabolic Heart Lab
Jiang Chang · College Station, Texas
Research Focus
Dr. Jiang Chang's lab focuses on understanding heart failure, particularly the metabolism of heart cells and how energy supply affects heart function. They are investigating a system called metabolic resuscitation, which could potentially be manipulated to improve treatments for heart failure. By using experimental approaches and animal models, the lab aims to identify new therapeutic strategies and biomarkers for heart failure management.
heart failuremetabolic resuscitationenergy metabolismanimal modelscardiac functiontherapeutic strategiesbiomarkersCRISPRcellular metabolismpatient outcomes
Research Aims
5AIM 01Explore the metabolic resuscitation system in heart failure.
AIM 02Define the functional significance of this resuscitative mechanism in the heart.
AIM 03Investigate the regulation of energy metabolism and its impact on heart function.
AIM 04Identify potential therapeutic targets for treating heart failure.
AIM 05Develop novel biomarkers for heart failure diagnosis and prevention.
Skills the Lab Values
CRISPR/Cas technologycell cultureanimal modelshistologyRNA analysismetabolic assaysPCRdata analysisgenetic modelingmicroscopy
Output against the department
Publications733top 3% of dept.30th of 1,033
this lab
most publishedleast published
Citations43ktop 6% of dept.63rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.