Princeton University · BiochemistryAntibiotic Resistance and Microbe-Host Interaction Lab
Zemer Gitai · Princeton, New Jersey
Research Focus
Professor Zemer Gitai's lab at Princeton University focuses on developing innovative strategies to tackle antibiotic resistance and enhance our understanding of microbe-host interactions. Using advanced techniques like single-cell RNA sequencing, the lab investigates how bacteria communicate with their hosts and seeks to create novel antibiotics and therapies that can help combat infections while minimizing resistance. This research combines expertise in microbiology, immunology, and computational biology to establish new methods for studying and manipulating bacterial behaviors.
antibiotic resistancesmall RNAsmicrobe-host interactionssingle-cell RNA sequencingphage therapy
Research Aims
5AIM 01Develop non-traditional antibiotics targeting resistant bacteria.
AIM 02Investigate the roles of small RNAs in microbe-host interactions.
AIM 03Understand the dynamics of phage therapy and its efficacy.
AIM 04Map sRNA-mediated interactions in the human gut microbiome.
AIM 05Create immune-modulating therapeutics based on sRNA functions.
Skills the Lab Values
single-cell RNA sequencingcell culturebacterial manipulationRNA interferencemammalian cell experimentation
Output against the department
Publications168bottom 48% of dept.207th of 402
this lab
most publishedleast published
Citations11ktop 46% of dept.185th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.