Northwestern University · Microbiology & ImmunologyPeptidoglycan Research Laboratory
Brandon Lyon Jutras · Evanston, Illinois
Research Focus
Dr. Brandon Lyon Jutras's lab focuses on understanding Lyme disease, particularly how a bacterial component called peptidoglycan can drive persistent symptoms in patients even after treatment. The lab investigates the unique properties of peptidoglycan from the bacterium Borrelia burgdorferi, which causes Lyme disease, to figure out its role in ongoing health issues like arthritis. By uncovering how and why peptidoglycan persists in the body, the research aims to develop better therapeutic strategies for Lyme disease patients whose symptoms persist post-antibiotic treatment.
Lyme diseasepeptidoglycanBorrelia burgdorferiLyme arthritischronic symptoms
Research Aims
5AIM 01Investigate the unique chemical properties of peptidoglycan in Borrelia burgdorferi
AIM 02Determine how peptidoglycan contributes to persistent Lyme disease symptoms
AIM 03Explore the relationship between host factors and peptidoglycan-induced arthritis
AIM 04Assess the viability of monoclonal antibody therapy for treating Lyme arthritis
AIM 05Characterize the persistence of peptidoglycan in patient samples after antibiotic treatment
Skills the Lab Values
PCRcell culturemouse modelsWestern blotimmunohistochemistry
Output against the department
Publications54bottom 13% of dept.421st of 486
this lab
most publishedleast published
Citations1.9kbottom 12% of dept.427th of 486
this lab
most citedleast cited
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