Florida Institute of Technology · EngineeringThe BreathSense Lab
Leslie Chan · Melbourne, Florida
Research Focus
Leslie Chan's lab at Georgia Tech focuses on developing innovative nanosensors that can be ingested to detect colorectal cancer through breath analysis. This technology aims to enhance early cancer detection in a non-invasive manner, making it easier for people to adhere to screening guidelines. By utilizing enzymatic activity in the intestines, these nanosensors will release detectable biomarkers in breath, potentially saving lives by catching cancer early.
nanosensorsbreath detectioncolorectal cancerearly diagnosisnon-invasive screening
Research Aims
5AIM 01Develop ingestible nanosensors for colorectal cancer detection.
AIM 02Engineer sensors to detect specific intestinal enzymes associated with tumor development.
AIM 03Create a breath biomarker signature for early-stage colorectal cancer.
AIM 04Test the efficacy of nanosensors in animal models.
AIM 05Advance non-invasive diagnostic technologies for gastrointestinal diseases.
Skills the Lab Values
nanosensor designmass spectrometryanimal modelsdrug delivery systemsbiomarker analysis