Harvard University · Microbiology & ImmunologyEddy Bioinformatics Lab
Sean R Eddy · Cambridge, Massachusetts
Research Focus
Dr. Sean R. Eddy's lab focuses on developing computational tools to analyze biological sequences and RNA structures. Their work is crucial for understanding evolutionary relationships among different life forms by leveraging large-scale genomic data. The lab's primary tools, HMMER and Infernal, help scientists find homologs of sequences more effectively, contributing to advancements in molecular biology and bioinformatics.
bioinformaticsHMMERInfernalcomputational biologysequence analysis
Research Aims
3AIM 01Develop a new Markov model to better distinguish homologs from nonhomologs
AIM 02Create efficient methods to summarize database search results
AIM 03Enhance computational strategies to utilize modern hardware for effective data processing
Skills the Lab Values
sequence alignmenthidden Markov modelsstochastic context-free grammarscomputational modelingdatabase management
Output against the department
Publications198top 33% of dept.158th of 486
this lab
most publishedleast published
Citations143ktop 1% of dept.2nd of 486
this lab
most citedleast cited
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