Northwestern University · PharmacologyKCNB1 Gene Research Lab
Jennifer A Kearney · Evanston, Illinois
Research Focus
Dr. Jennifer Kearney's lab focuses on understanding a specific genetic cause of severe developmental disorders and epilepsy. They study the KCNB1 gene, which is linked to a range of neurological issues, including developmental delays and challenging-to-treat seizures in children. By analyzing the effects of various mutations in this gene, the lab aims to uncover the mechanisms behind these conditions and to pave the way for better treatments.
KCNB1epilepsydevelopmental disordersion channelsgenetic variants
Research Aims
3AIM 01Investigate how KCNB1 variants are expressed at the plasma membrane.
AIM 02Explore the classical ion conducting functions of KCNB1 variants.
AIM 03Analyze the non-canonical signaling functions of KCNB1 variants.
Skills the Lab Values
cell cultureelectrophysiologyflow cytometryimmunocytochemistryhigh-throughput screening
Output against the department
Publications122bottom 35% of dept.299th of 462
this lab
most publishedleast published
Citations4.9kbottom 37% of dept.293rd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.